Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - Androgen Receptor (AR) - Leelamine hydrochloride

Leelamine hydrochloride

CAS No. 16496-99-4

Leelamine hydrochloride( Dehydroabietylamine )

Catalog No. M12521 CAS No. 16496-99-4

Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Leelamine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR).
  • Description
    Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR), inhibits castration-resistant prostate cancer cells; causes apoptosis and suppresses 22Rv1 xenograft growth in vivo; Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Dehydroabietylamine
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    Androgen Receptor (AR)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    16496-99-4
  • Formula Weight
    321.933
  • Molecular Formula
    C20H32ClN
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (77.66 mM)
  • SMILES
    CC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)CN)C.Cl
  • Chemical Name
    1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine, monohydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Singh KB, et al. Mol Cancer Ther. 2018 Jul 20. pii: molcanther.0117.2018. 2. Gowda R, et al. Oncotarget. 2017 Apr 25;8(17):28260-28277. 3. Sehrawat A, et al. Mol Carcinog. 2017 Feb;56(2):337-348. 4. Kuzu OF, et al. Mol Cancer Ther. 2014 Jul;13(7):1690-703.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • AR antagonist 1

    AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.

  • Enobosarm

    Enobosarm (GTx-024, MK-2866, Ostarine) is a selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and osteoporosis.

  • BMS-641988 B

    BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.

Sign In Join Free